Emerging Variant Glioma: Glioblastoma with a Primitive Neuro-Ectodermal Tumor(PNET) Component

Glioblastoma with a PNET component - Report of an emerging variant with therapeutic and prognostic implications.

Advances in managing medulloblastoma and intracranial primitive neuro-ectodermal tumors

Medulloblastoma and central nervous system (CNS)-primitive neuro-ectodermal tumors (PNETs) are a diverse group of entities which encompasses different pathological and clinical pictures. Initially divided based on histology and location, molecular insight is leading to new definitions and a change in the borders delineating these diseases, such that they become more divergent. Current treatment...

Primitive Neuro Ectodermal Tumor Arising in a Testicular Teratoma with Retroperitoneal Metastasis: A Case Report and Review of Literature

A 38-year-old man presenting with left testicular mass and extensive retroperitoneal lymphadenopathy underwent radical orchiectomy and specimen showed a germ cell tumor of primarily primitive neuroectodermal tumor mixed with mature teratoma. He then underwent RPLND, followed by adjuvant CAV (cyclophosphamide, doxorubicin, vincristine) and IE (ifosfamide, etoposide) alternating chemotherapy give...

Glioblastoma with primitive neuronal component: report of a case and review of literature

According to the 2016 WHO Classification, glioblastoma with primitive neuronal components (GBM-PNC) was added as a pattern in glioblastoma. A 59-year-old woman presented initially with paroxysmal headache at bilateral frontal temporal for a month. Imaging showed a solid cystic mass in the right frontal lobe with a range of 4.7 cm×5.6 cm. She had an operation to excise the occupying lesion in th...

Ganglioglioma with glioblastoma component.

Ganglioglioma with a glioblastomatous component and high-grade atypia of neuronal cells are extremely rare findings. In this paper, we report the case of a 60-year-old man who presented with a tumor of the left temporal lobe. Hematoxylin-Eosin stained slides revealed a complex tumor with features of glioblastoma and marked atypia of neuronal cells. Glial cells were highlightened by antibodies t...